Brooklyn College Library LibGuides Home: BIOL 3011: Genetics (Gotesman): Unit 7: DNA Mutation Analysis

Topics for Unit 7: DNA Mutation Analysis

Lecture 14: Mechanism of mutation, complementation analysis

Lecture 15: Impact of DNA Mutations

At the end of this unit you should be able to:

Demonstrate ability to analyze data presented in tabular and graphic format
Demonstrate ability to order biochemical intermediates into a biochemical pathway and determine the effect of mutations on the progression of the pathway
Demonstrate ability to determine how many genes are involved in a pathway
Demonstrate understanding of the concept of complementation analysis and solve complementation problems

Readings: Mechanism of mutation, complementation analysis (Unit 7)

Genetic mutation (external link)
Loewe, L. (2008) Genetic mutation. Nature Education 1(1):113

Videos: Mechanism of mutation, complementation analysis (Unit 7)

Module 7: Mechanisms of Inheritance

Professor Rosie Redfield, The University of British Columbia

Watch the entire Module 7: Mechanisms of Inheritance playlist, consisting of 19 parts.

Attribution:
[Useful Genetics] (2015, Aug. 10 & Aug. 23) Module 7: Mechanisms of Inheritance [Video File.] Retrieved from https://www.youtube.com/playlist?list=PLgh8WcYegg44v3l2j1I0cAoYhem_eqeEo

Readings: Impact of DNA Mutations (Unit 7)

The Ames Test (pdf)
De Stasio, E. (2017). The Ames Test. [online] Genetics.org. Available at: http://www.genetics-gsa.org/education/pdf/GSA_DeStasio_Ames_Student_Resources.pdf [Accessed 19 Feb 2018].