Brooklyn College Library LibGuides Home: BIOL 3011: Genetics (Gotesman): Unit 5: Chromosome Mapping

Topics for Unit 5: Chromosome Mapping

Lecture 10: Gene Linkage and Recombination for chromosome mapping

Lecture 11: Tetrad Analysis, Mitotic Recombination and Genetic Mosaics

At the end of this unit you should be able to:

Understand the difference in inheritance patterns between independently assorting genes and linked genes
Understand the assumptions that are used to develop mapping functions
Understand there is a relationship between genetic distance between genes and physical distance
Understand the assumptions used in the analysis of three-gene test crosses and compute the outcomes of three-point test crosses by solving word problems
Understand that the biology of an organism must be understood in order to map genes on achromosome

Thomas Hunt Morgan, Genetic Recombination, and Gene Mapping (external link)
Lobo, I. & Shaw, K. (2008) Thomas Hunt Morgan, genetic recombination, and gene mapping. Nature Education 1(1):205
Gene Mapping and Disease (external link)
Chial, H. (2008) Gene mapping and disease. Nature Education 1(1):50
How do you map a genome? (external link)
yourgenome, (2016). How do you map a genome? [online] Available at: https://www.yourgenome.org/facts/how-do-you-map-a-genome [Accessed 16 June 2016].

Linkage and tetrad analysis in yeast (external link)
Vallabh Minikel, Eric (2014, Sep 8) Genetics 03: 'Linkage and tetrad analysis in yeast'. Retrieved from: http://www.cureffi.org/2014/09/08/genetics-03/
Tetrad Analysis (external link)
(2008) Tetrad Analysis. In: Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer, Dordrecht Retrieved from https://doi.org/10.1007/978-1-4020-6754-9